[Plantsci] SPLS Tuesday Seminar – Today - Cristian Salazar De Leon, University of Arizona

[Xiong, Zhongguo - (zxiong)]

Dear all,

Please join us in Marley 230<https://map.arizona.edu/107> at 4:00 PM today for a seminar presented by Cristian Salazar De Leon, School of Plant Sciences, University of Arizona. Dr. Jesse Woodson will serve as the host.

Zoom link: https://arizona.zoom.us/j/84253432688  (password: SPLS2025).
Refreshments will be provided in the Marley Lobby at 3:30 PM.

Title: Role of inosine 5’-monophosphate dehydrogenase in 1O2 signaling in Arabidopsis thaliana

Abstract: Plants are sessile organisms and have evolved cellular mechanisms to sense and respond to their environment. One way they can do this is through their energy producing organelles, which produce steady-state levels of reactive oxygen species (ROS). Increased levels of ROS can indicate changes or stressors in their environment and act as signals that trigger a cellular response. Specifically, the chloroplast produces a type of ROS called singlet oxygen (1O2), which acts as a retrograde signal from the chloroplast to the nucleus to initiate a transcriptional response to stress. Chloroplast 1O2 retrograde signaling can be monitored in the Arabidopsis thaliana plastid ferrochelatase two (fc2) mutant, which produces a burst of 1O2 in the chloroplast under cycling light conditions causing rapid chloroplast degradation and cell death. A genetic suppressor screen for mutants that rescued the fc2 phenotype which identified 24 ferrochelatase two suppressor (fts) candidates. Two of these fts mutants (fts2 & fts13) affect a nucleotide metabolism gene, inosine 5’-monophosphate dehydrogenase 1 (impdh1), which encodes one of two cytoplasmic enzymes necessary for de novo guanosine monophosphate (GMP) synthesis. My research project aims to understand the role of impdh1 in 1O2 signaling in Arabidopsis thaliana.

This will be the final seminar of the semester. Thank you all for your participation throughout the semester, and I wish everyone a smooth and successful finals week.

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Zhongguo Xiong
School of Plant Sciences       BIO5 Institute
BIO5                           Email: zxiong at arizona.edu<mailto:zxiong at arizona.edu>
                               Phone: (520)-621-9869
Forbes 303, P.O. box 210036    Fax: (520)-621-7186
University of Arizona
Tucson, AZ 85721-0036          http://ag.arizona.edu/~zxiong
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