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<span style="background-color: white;">Dear all,</span></div>
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<span style="font-family: "Times New Roman", serif; font-size: 14pt; color: black;">Please join us! We have the pleasure of welcoming Dr. Tessa Burch-Smith who is visiting from the
<a href="https://www.danforthcenter.org/our-work/principal-investigators/tessa-burch-smith/" id="LPlnk" title="https://www.danforthcenter.org/our-work/principal-investigators/tessa-burch-smith/" style="margin-top: 0px; margin-bottom: 0px;">
Donald Danford Plant Science Center</a> for her seminar presentation as part of our SPLS seminar series:</span></p>
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<div style="margin-right:12px;height:160px;overflow:hidden"><a target="_blank" href="https://www.danforthcenter.org/our-work/principal-investigators/tessa-burch-smith/" data-loopstyle="linkonly" class="OWAAutoLink" id="OWA746ee569-df87-baae-ccc5-7af29a398ea0"><img alt="" height="160" style="display:block" width="160" src="https://www.danforthcenter.org/wp-content/uploads/2021/08/Dr.-Tessa-Burch-Smith.jpg"></a></div>
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<a target="_blank" href="https://www.danforthcenter.org/our-work/principal-investigators/tessa-burch-smith/" style="text-decoration:none" data-loopstyle="linkonly" class="OWAAutoLink" id="OWAa80caa1e-88ea-744f-5fea-ddd72263ffbc">Dr. Tessa Burch-Smith | Principal
Investigator | Danforth Center</a></div>
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Dr. Tessa Burch-Smith is an Associate Member at the Donald Danforth Plant Science Center. Learn more about her plant science research.</div>
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www.danforthcenter.org</div>
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<span style="font-family: "Times New Roman", serif; font-size: 14pt; color: rgb(0, 0, 0); font-weight: 700;">“Insights into regulating intercellular communication via plasmodesmata”</span></p>
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<span style="font-family: "Times New Roman", serif; font-size: 14pt; color: black;"><b>Tuesday, April 9th, 2024</b></span></p>
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<p align="center" style="direction: ltr; margin-top: 0px; margin-bottom: 0px;"><span style="font-family: "Times New Roman", serif; font-size: 14pt; color: black;"><b>Marley 230</b></span></p>
<p align="center" style="direction: ltr; margin-top: 0px; margin-bottom: 0px;"><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(33, 33, 33);"><i>Refreshments served in Marley lobby at 3:30pm.</i></span></p>
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<p align="center" style="direction: ltr; margin-top: 0px; margin-bottom: 0px;"><span style="font-family: "Times New Roman", serif; font-size: 14pt; color: black;">Zoom:</span></p>
<p align="center" style="direction: ltr; margin-top: 0px; margin-bottom: 0px;"><span style="font-family: "Times New Roman", serif; font-size: 14pt; color: rgb(0, 120, 215);"><a href="https://arizona.zoom.us/j/83044711714" id="OWAadc48525-171f-4479-7382-e273ab99b3f4" class="x_OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly" style="color: rgb(0, 120, 215); margin-top: 0px; margin-bottom: 0px;">https://arizona.zoom.us/j/83044711714</a></span></p>
<p align="center" style="direction: ltr; margin-top: 0px; margin-bottom: 0px;"><span style="font-family: "Times New Roman", serif; font-size: 14pt; color: black;">(password: spls23)</span></p>
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<span style="font-family: "Times New Roman", serif; color: black;"><b><i>Abstract: </i></b></span></p>
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<span style="font-family: "Times New Roman", Times, serif; font-size: 12pt; color: rgb(33, 33, 33);"><i>Plasmodesmata (PD) link the cytoplasm of two adjacent cells, allowing intercellular trafficking of solutes, signaling molecules, protein, RNA and ribonucleoprotein
complexes. The regulation of plasmodesmata-mediated trafficking is essential for plant growth and development. A hypothesis called Organelle-nucleus-plasmodesmata-signaling (ONPS) developed by our group posits that specific changes in organellar (plastids
or mitochondria) state lead to signaling to the nucleus (chloroplast-to-nucleus retrograde signaling, CRS) which tunes expression of nucleus-encoded genes associated with plasmodesmal regulation. Investigation of known signaling pathways involved in chloroplast-to-nucleus
retrograde signaling suggests that these pathways are also involved in regulating plasmodesmata. Indeed, we have found that intermediates in the tetrapyrrole biosynthetic pathway may have an important role in ONPS. In the Arabidopsis thaliana ise2 mutant,
there is increased intercellular trafficking and increased numbers of branched PD. Gene expression analyses in A. thaliana embryos and plants with reduced ISE2 expression identified genes associated with glucosinolate biosynthesis and metabolism as highly
affected by changes in ISE2 expression. Further investigations have revealed a role for aliphatic glucosinolates in mediating ISE2’s effects on intercellular trafficking. Together, these studies reveal complexity in the cellular signaling mechanisms that
regulate intercellular trafficking and illuminate the important roles of metabolites in signaling. </i></span></p>
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<span style="font-family: "Times New Roman", serif; font-size: 18.666666px; color: rgb(0, 0, 0); background-color: rgb(255, 255, 255);"><img id="image_0" width="740" height="556" style="width: 740px; height: 556px; margin: 0px; vertical-align: top;" data-outlook-trace="F:1|T:1" src="cid:98a5a050-0a61-428b-867b-a9de66d9432e"></span></p>
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<p style="direction: ltr; text-align: left; margin: 0in;"><span style="font-family: "Times New Roman", serif; font-size: 12pt; color: rgb(0, 0, 0); background-color: rgb(255, 255, 255);">Thank you and I look forward to seeing you there,</span></p>
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<p style="direction: ltr; text-align: left; margin: 0in;"><span style="font-family: "Times New Roman", serif; font-size: 12pt; color: rgb(0, 0, 0); background-color: rgb(255, 255, 255);">Keenia</span></p>
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<p style="margin-top: 0px; margin-bottom: 0px;"><span style="font-family: "Edwardian Script ITC"; font-size: 18pt; color: rgb(23, 78, 134);"><b>Keenia Shinagawa, M. Ed.
</b></span><span style="font-family: "Times New Roman", serif; font-size: 10pt; color: rgb(73, 80, 87);">she/her</span></p>
<p style="margin-top: 0px; margin-bottom: 0px;"><span style="font-family: "Times New Roman", serif; font-size: 10pt; color: rgb(118, 62, 155); background-color: rgb(255, 255, 255);"><b><i>Student Support | Graduate Coordinator</i></b></span></p>
<p style="margin-top: 0px; margin-bottom: 0px;"><span style="font-family: "Times New Roman", serif; font-size: 9pt; color: rgb(200, 38, 19); background-color: rgb(255, 255, 255);"><b>THE UNIVERSITY OF ARIZONA</b></span></p>
<p style="text-align: left; background-color: rgb(255, 255, 255); margin: 0in;"><span style="font-family: "Times New Roman", serif; font-size: 10pt; color: rgb(111, 192, 64);"><i>School of Plant Sciences (SPLS)</i></span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(13, 13, 13);"><br>
</span><span style="font-family: "Times New Roman", serif; font-size: 10pt; color: rgb(12, 136, 42);"><i>College of Ag., Life & Environ. Sci (CALES)</i></span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(13, 13, 13);"><br>
</span><span style="font-family: "Times New Roman", serif; font-size: 10pt; color: rgb(81, 167, 249);">Office:
<b>Forbes, 317</b><br>
PO Box 210036 | Tucson, AZ 85721</span></p>
<p style="text-align: left; background-color: rgb(255, 255, 255); margin: 0in;"><span style="font-family: "Times New Roman", serif; font-size: 10pt; color: rgb(81, 167, 249);">O: (520) 621-1336</span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(13, 13, 13);"><br>
<a href="mailto:kshinagawa@arizona.edu" id="OWA984147e1-f5a0-fa06-4080-54dd7a3b53e5" class="OWAAutoLink" data-loopstyle="linkonly" style="margin: 0px;">kshinagawa@arizona.edu</a><br>
</span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(139, 0, 21);"><b><a href="https://www.arizona.edu/" id="OWAa81040c7-9136-3ee6-0a98-445941652414" class="OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly" style="margin: 0px;">www.arizona.edu</a></b></span></p>
<p style="text-align: left; background-color: rgb(255, 255, 255); margin: 0in;"><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(139, 0, 21);"><a href="https://www.facebook.com/UASchoolofPlantSciences" id="OWA8ab6c452-2a90-90d0-a1cd-d083db93eec5" class="OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly" style="margin: 0px;">facebook</a></span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(118, 118, 118);"> |
</span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(139, 0, 21);"><a href="https://twitter.com/UAPlantSciences" id="OWA08870d3b-6081-5c22-dfc3-7fdc1da858bb" class="OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly" style="margin: 0px;">twitter</a></span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(118, 118, 118);"> |
</span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(139, 0, 21);"><a href="https://www.instagram.com/uarizona" id="OWA2bdc7a06-0292-d32f-566c-c310a6513525" class="OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly" style="margin: 0px;">instagram</a></span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(118, 118, 118);"> |
</span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(139, 0, 21);"><a href="https://www.linkedin.com/school/the-university-of-arizona" id="OWAa38555d1-61dd-d85a-f6f3-4e231d0fdb04" class="OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly" style="margin: 0px;">linkedin</a></span></p>
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<p style="text-align: left; background-color: rgb(255, 255, 255); margin: 0in;"><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(190, 91, 23);">Student Resources:</span></p>
<p style="text-align: left; background-color: rgb(255, 255, 255); margin: 0in;"><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(0, 0, 0);"><a href="https://cals.arizona.edu/life-management-services" id="OWA78a73cfd-5aed-600f-ca44-91ba58b1b9c1" class="OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly" style="margin: 0px;">CALS
Life Management Counselors</a> </span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(73, 80, 87);">|
</span><span style="font-family: "Times New Roman", serif; font-size: 11pt; color: rgb(0, 0, 0);"><a href="https://cals.arizona.edu/learning-lab" id="OWA133e9fe0-6f00-904f-6b03-91cd84ba1094" class="OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly" style="margin: 0px;">CALS
Learning Lab</a> | <a href="https://grad.arizona.edu/gsas/gradpath/gradpath-user-guides" id="OWA54ef8e04-2fc8-b200-cf3b-3376f75e60a7" class="OWAAutoLink" title="https://grad.arizona.edu/gsas/gradpath/gradpath-user-guides" data-auth="NotApplicable" data-loopstyle="linkonly" style="margin-top: 0px; margin-bottom: 0px;">
Grad Path User Guides</a></span></p>
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