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Dear SPLS graduate students,</div>
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<span style="font-size: 12pt;">I am hosting next week's SPLS seminar speaker </span>
<span style="font-size: 16px;"><a href="https://www.danforthcenter.org/our-work/principal-investigators/tessa-burch-smith/" id="OWAd4a6307b-284e-5f1a-3cdc-fd21a91b6fb4" class="OWAAutoLink" title="https://www.danforthcenter.org/our-work/principal-investigators/tessa-burch-smith/" data-auth="NotApplicable" data-loopstyle="linkonly" style="margin: 0px; text-align: left;">Dr.
Tessa Burch-Smith from the Danforth Center</a></span></div>
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Her work broadly revolves around cell-to-cell signaling in plants during stress and infection. I expect a fantastic seminar and urge everyone to attend.</div>
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If you can, please <a href="https://docs.google.com/spreadsheets/d/1IJErwqFLiroxAa0wtINzQJT8F5KekCw8AkEvuv4UzTo/edit?usp=sharing" id="OWA25dcca32-d05e-61f2-dd0e-22a963e5e1e1" class="OWAAutoLink" title="https://docs.google.com/spreadsheets/d/1IJErwqFLiroxAa0wtINzQJT8F5KekCw8AkEvuv4UzTo/edit?usp=sharing" data-auth="NotApplicable" data-loopstyle="linkonly" style="margin: 0px;">
sign up</a> to have lunch with her on Tuesday April 9.</div>
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Thank you and please let me know if you have any questions.</div>
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Best,</div>
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-Jesse</div>
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Dr. Tessa Burch-Smith - Associate member, Danforth Center</div>
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Seminar Tuesday April 9, 4:00 PM - Marley 230 (Zoom link will also be provided</div>
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<b><i><br>
Title: Insights into regulating intercellular communication via plasmodesmata</i></b></div>
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<span style="font-family: "Times New Roman", serif; font-size: 12pt; color: rgb(0, 0, 0); line-height: 17.120001px;">Plasmodesmata (PD) link the cytoplasm of two adjacent cells, allowing intercellular trafficking of solutes, signaling molecules, protein, RNA
and ribonucleoprotein complexes. The regulation of plasmodesmata-mediated trafficking is essential for plant growth and development. A hypothesis called Organelle-nucleus-plasmodesmata-signaling (ONPS) developed by our group posits that specific changes in
organellar (plastids or mitochondria) state lead to signaling to the nucleus (chloroplast-to-nucleus retrograde signaling, CRS) which tunes expression of nucleus-encoded genes associated with plasmodesmal regulation. Investigation of known signaling pathways
involved in chloroplast-to-nucleus retrograde signaling suggests that these pathways are also involved in regulating plasmodesmata. Indeed, we have found that intermediates in the tetrapyrrole biosynthetic pathway may have an important role in ONPS. In the
<i>Arabidopsis thaliana ise2 </i>mutant,<i> </i>there is increased intercellular trafficking and increased numbers of branched PD. Gene expression analyses in
<i>A. thaliana</i> embryos and plants with reduced <i>ISE2 </i>expression identified genes associated with glucosinolate biosynthesis and metabolism as highly affected by changes in
<i>ISE2</i> expression. Further investigations have revealed a role for aliphatic glucosinolates in mediating ISE2’s effects on intercellular trafficking. Together, these studies reveal complexity in the cellular signaling mechanisms that regulate intercellular
trafficking and illuminate the important roles of metabolites in signaling. </span></p>
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Jesse Woodson, PhD<br>
Associate Professor, School of Plant Sciences<br>
University of Arizona<br>
Office: Marley 541E</div>
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Office phone: (520) 621-3970</div>
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Lab phone: (520) 621-4746</div>
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<a href="https://cals.arizona.edu/spls/content/jesse" id="LPlnk685644" class="OWAAutoLink" title="https://cals.arizona.edu/spls/content/jesse
Cmd+Click or tap to follow the link" data-auth="NotApplicable" data-loopstyle="linkonly">https://cals.arizona.edu/spls/content/jesse</a></div>
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<u>Mailing address:</u><br>
303 Forbes Hall<br>
1140 E. South Campus Drive<br>
University of Arizona<br>
Tucson, AZ 85721-0036</div>
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