<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=Windows-1252">
<meta name="Generator" content="Microsoft Word 15 (filtered medium)">
<style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:DengXian;
panose-1:2 1 6 0 3 1 1 1 1 1;}
@font-face
{font-family:Aptos;}
@font-face
{font-family:"\@DengXian";
panose-1:2 1 6 0 3 1 1 1 1 1;}
@font-face
{font-family:"Vladimir Script";
panose-1:3 5 4 2 4 4 7 7 3 5;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0in;
font-size:12.0pt;
font-family:"Aptos",sans-serif;
mso-ligatures:standardcontextual;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#467886;
text-decoration:underline;}
span.EmailStyle17
{mso-style-type:personal-compose;
font-family:"Aptos",sans-serif;
color:windowtext;}
.MsoChpDefault
{mso-style-type:export-only;}
@page WordSection1
{size:8.5in 11.0in;
margin:1.0in 1.0in 1.0in 1.0in;}
div.WordSection1
{page:WordSection1;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
</head>
<body lang="EN-US" link="#467886" vlink="#96607D" style="word-wrap:break-word">
<div class="WordSection1">
<p class="MsoNormal"><span style="font-size:11.0pt">Hi all,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt">This is a quick reminder for today’s seminar in Marley 230 at 4:00 PM, presented by Dr. David Baltrus.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><a href="https://arizona.zoom.us/j/83044711714?pwd=IQ994mWIPwbsRKMnfF9sERx5sNtv4m.1">Zoom link</a>:
<a href="https://arizona.zoom.us/j/83044711714">https://arizona.zoom.us/j/83044711714</a> (password: SPLS24).<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Refreshments will be provided in the Marley Lobby at 3:30 PM.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt">Developing LPS-targeting bacteriocins as strain specific antibacterials
<o:p></o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt">Abstract</span></b><span style="font-size:11.0pt">: Since interactions between microbes can determine assembly dynamics within microbiomes, outcomes of these interactions have the potential to directly
shape functional outputs of microbial communities. A deeper understanding of the molecules that drive these interactions may therefore enable fine scale manipulation of microbiomes in both clinical and agricultural settings. Over the last decade, the Baltrus
lab has discovered and characterized a variety of molecules produced by bacterial phytopathogens, including tailocins (which are antimicrobials derived from phage tails), which are highly specific and can be used to target and kill numerous agriculturally
relevant pathogens. We have further developed multiple assays to characterize the genetic and genomic basis of tailocin production and sensitivity, and we have demonstrated that the lipopolysaccharide layer is the likely the binding site for tailocins. Lastly,
we demonstrate the potential for these molecules to be developed into prophylactic antibiotics to protect crops from colonization by clinical and agricultural pathogens.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal" style="margin-bottom:12.0pt"><span style="font-size:10.0pt;font-family:"Courier New";mso-ligatures:none">===============================================================<br>
</span><b><span style="font-size:20.0pt;font-family:"Vladimir Script";mso-ligatures:none">Zhongguo Xiong</span></b><span style="font-size:10.0pt;font-family:"Courier New";mso-ligatures:none"> <br>
School of Plant Sciences BIO5 Institute<br>
BIO5 Email: <span style="color:blue"><a href="mailto:zxiong@arizona.edu"><span style="color:blue">zxiong@arizona.edu</span></a></span>
<br>
Phone: (520)-621-9869<br>
Forbes 303, P.O. box 210036 Fax: (520)-621-7186<br>
University of Arizona <br>
Tucson, AZ 85721-0036 <span style="color:blue"><a href="http://ag.arizona.edu/~zxiong"><span style="color:blue">http://ag.arizona.edu/~zxiong</span></a></span><br>
===============================================================</span><span style="font-size:11.0pt;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
</body>
</html>