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<p class="MsoNormal">Good morning everyone,<o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif">Reminder: Tomorrow is our Summer Series Seminar – Towards a Joint Center for Sustainable Agriculture in Desert Environments. Join us!<o:p></o:p></span></p>
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<p class="MsoNormal"><img width="1" height="1" style="width:.0104in;height:.0104in" id="_x0000_i1048" src="https://images.e2ma.net/images/spacer.gif" alt="Tuesday, June 22"><o:p></o:p></p>
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<p class="MsoNormal"><span style="font-size:11.5pt;font-family:"Arial",sans-serif;color:#2A809F">Thursday, June 17<o:p></o:p></span></p>
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<h1 style="margin:0in;vertical-align:baseline"><span style="font-size:19.0pt;font-family:"Arial",sans-serif;color:#2A809F">CDA seminar: Salim Al-Babili and Monica Schmidt<o:p></o:p></span></h1>
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<p class="MsoNormal"><strong><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black">Tuesday, June 22, 2021</span></strong><b><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black"><br>
<strong><span style="font-family:"Arial",sans-serif">7:00 – 8:30 p.m. (AST)</span></strong><br>
<strong><span style="font-family:"Arial",sans-serif">On Zoom</span></strong><br>
<strong><span style="font-family:"Arial",sans-serif">Password: 905015</span></strong></span></b><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black"><o:p></o:p></span></p>
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<h4 style="margin:0in;vertical-align:baseline"><strong><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#1DA6A9">Carotenoid Metabolism: A Mine for Plant Growth Regulators</span></strong><span style="font-size:8.5pt;font-family:"Arial",sans-serif;color:#333333;font-weight:normal"><o:p></o:p></span></h4>
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<p class="MsoNormal"><span class="e2ma-style"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222">By
</span></span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black">Salim Al-Babili<br>
</span><span class="e2ma-style"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222">Professor of Plant Science, KAUST</span></span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black"><o:p></o:p></span></p>
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<h3 style="margin:0in;vertical-align:baseline"><span class="e2ma-style"><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#01A9E7">Abstract</span></span><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#1DA6A9"><o:p></o:p></span></h3>
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<p class="MsoNormal" style="line-height:16.9pt;background:white"><span class="e2ma-style"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222">The breakdown of carotenoids is the initial step in the formation of known plant hormones,
such as strigolactones, and of yet-unidentified carotenoid-derivatives, apocarotenoids, supposed to regulate plant growth and development. In the last years, we have been focusing on strigolactone biosynthesis and on the discovery of novel apocarotenoid growth
regulators.</span></span><span style="font-size:11.5pt;font-family:"Verdana",sans-serif;color:#222222"><o:p></o:p></span></p>
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<p class="MsoNormal" style="line-height:16.9pt;background:white"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222">For this purpose, we study the activity of carotenoid modifying enzymes, generate and phenotype corresponding mutants
and test the activity of known and presumed carotenoid cleavage products. In this talk, I will describe the discovery of anchorene, a carotenoid-derived di-aldehyde, as the specific signal needed for the formation of anchor roots in Arabidopsis, and present
our results about zaxinone, a candidate for a novel plant hormone that promotes rice growth and determines its hormone homeostasis and architecture. Finally, I will briefly present how we translate our findings into agricultural applications, such as combating
the root parasitic plant Striga, a major threat to global food security.</span><span style="font-size:11.5pt;font-family:"Verdana",sans-serif;color:#222222">
<o:p></o:p></span></p>
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<h3 style="margin:0in;vertical-align:baseline"><span class="e2ma-style"><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#01A9E7">About the speaker</span></span><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#1DA6A9"><o:p></o:p></span></h3>
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<p class="MsoNormal" style="line-height:15.75pt;background:white"><span class="e2ma-style"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222;background:white">Salim Al-Babili received his Ph.D. from the University of Freiburg, Germany.
After his Ph.D., he obtained a Rockefeller post-doc fellowship to develop Golden Rice in the lab of Peter Beyer and in collaboration with the group of Ingo Potrykus. In 2007, he received his Habilitation in Cell Biology at the University of Freiburg and is
currently Professor for Bioscience at King Abdullah University of Science and Technology (KAUST). The general objective of his research group is to improve the performance and nutritional value of crops by genetic engineering or by developing hormone-based
approaches.</span></span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black"><o:p></o:p></span></p>
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<p class="MsoNormal" style="line-height:15.75pt;background:white"><span class="e2ma-style"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222;background:white">His lab combines metabolomics with enzymology-based and genetic approaches
to elucidate metabolic networks and identify new signaling molecules related to abiotic/biotic stress response and plant development. He has made essential contributions to engineering crops with enhanced pro-vitamin A content and the elucidation of carotenoid/apocarotenoid
metabolism in plants and microorganisms. His discovery of the metabolite carlactone deciphered the core pathway in the biosynthesis of the plant hormone strigolactone. He is currently heading an international consortium funded by the Bill & Melinda Gates Foundation
to combat the root parasitic plant </span></span><em><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black">Striga hermonthica</span></em><span class="e2ma-style"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222;background:white">,
a major threat to global food security, in sub-Saharan Africa. </span></span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black">
<o:p></o:p></span></p>
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<h3 style="margin:0in;vertical-align:baseline"><strong><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#1DA6A9">Engineering functional foods</span></strong><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#1DA6A9"><o:p></o:p></span></h3>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black">By Monica Schmidt <br>
</span><span class="e2ma-style"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222;background:white">Associate Professor, School of Plant Sciences, University of Arizona</span></span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black"><o:p></o:p></span></p>
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<h3 style="margin:0in;vertical-align:baseline"><span class="e2ma-style"><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#01A9E7">Abstract</span></span><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#1DA6A9"><o:p></o:p></span></h3>
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<p class="MsoNormal" style="line-height:16.9pt;background:white"><span class="e2ma-style"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222">An overview of some of the functional food and functional genomic projects that are ongoing
in the laboratory will be presented. Strategies to enhance the nutrition of food/feed items include both the addition of compounds and/or the elimination of compounds. Pioneering efforts to reduce/eliminate contaminating fungal-produced aflatoxin in crops
using RNAi suppression are currently being coupled with toxin-degradation strategies during both pre- and post-harvest conditions to recover the millions of tons lost due to this carcinogenic compound. The addition of nutraceutical carotenoids in seeds has
been successful in many crop species.</span></span><span style="font-size:11.5pt;font-family:"Verdana",sans-serif;color:#222222"><o:p></o:p></span></p>
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<p class="MsoNormal" style="margin-bottom:12.0pt;line-height:16.9pt"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black">There are over 700 carotenoids in nature with six of these colorful compounds displaying health benefits. Seed-specific
metabolic engineering strategies were successful at the biofortification of the eye-healthy carotenoids, B-carotene and zeaxanthin, as well as the potent antioxidant and fish colorant, astaxanthin, in soybean, brassica or Camelina sativa seeds. Interestingly,
seeds with enhanced carotenoid content have an elevated protein content, likely due to altered levels of the carotenoid-derived phytohormone abscisic acid. Functional genomic projects are on-going for candidate genes involved in this pathway to create enhanced
protein without modified carotenoid content. Currently, the world health organization estimates a third of the world’s children suffer from protein deficiency. Strategies to engineer or breed enhanced protein content in crops should have a significant role
in alleviating nutritional deficiencies. <o:p></o:p></span></p>
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<h3 style="margin:0in;vertical-align:baseline"><span class="e2ma-style"><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#01A9E7">About the Speaker</span></span><span style="font-size:14.5pt;font-family:"Arial",sans-serif;color:#1DA6A9"><o:p></o:p></span></h3>
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<p class="MsoNormal" style="line-height:16.9pt;background:white"><span class="e2ma-style"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222">Monica Schmidt received her BSc from The University of Windsor and her Ph.D. in Genetics from
The University of British Columbia, followed by post-doctorate positions at The University of Georgia and the USDA at The Danforth Plant Science Center. She participates in the development of solutions to some of the major global agricultural problems. She
works on enhancing seed traits in two of the most globally important crops, soybean and corn. Her research program leverages basic plant science to produce biotechnology output traits that enhance nutrition and food safety in crops. She colloquially describes
her research program as functional foods; extending food/feed function beyond the delivery of mere calories for the benefit of the consumer.</span></span><span style="font-size:11.5pt;font-family:"Verdana",sans-serif;color:#222222"><o:p></o:p></span></p>
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<p class="MsoNormal" style="line-height:16.9pt"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black">Her research interests have two primary goals: enhancing food items through metabolic engineering, and assessing the genetic risk underlying
biotechnology techniques. Soybean production will need to double by 2050, making this crop an ideal vehicle for biotechnological strategies to create new varieties to serve as protein factories to produce better food, feed, and industrial proteins, as well
as to produce modified oils. She has worked on the fortification of soybean seeds with nutritionally beneficial carotenoids as well as enhancement of overall protein content. Her efforts in maize have largely focused on the recovery of crop losses due to toxic
secondary compounds produced from contaminating fungal species. Her research efforts should have a significant impact on the success/acceptance of the next wave of biotechnology, known as the second green revolution, by focusing on the enhancement of crops
for the betterment of humankind and impacting global food safety and security. </span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#222222;background:white"><br>
</span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black"><br>
Part of the KAUST - University of Arizona summer seminar series – Towards a Joint Center for Sustainable Agriculture in Desert Environments. <a href="https://urldefense.com/v3/__https:/t.e2ma.net/click/crzhpg/wm13qnb/guoubfb__;!!Nmw4Hv0!loczJd6MKO2F_4iWpmFhMH9zetaPjpz1613cEofZnaJG-FFV4a_EU54qHzzLsv6Ffhs$"><span style="color:#01A9E7;text-decoration:none">Click
here</span></a> to view the full schedule.<o:p></o:p></span></p>
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<p class="MsoNormal" style="line-height:15.75pt"><strong><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black">Brought to you by the <a href="https://urldefense.com/v3/__https:/t.e2ma.net/click/crzhpg/wm13qnb/wmpubfb__;!!Nmw4Hv0!loczJd6MKO2F_4iWpmFhMH9zetaPjpz1613cEofZnaJG-FFV4a_EU54qHzzLn4rWbwk$"><span style="color:#01A9E7;font-weight:normal;text-decoration:none">Center
for Desert Agriculture.</span></a></span></strong><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black"><o:p></o:p></span></p>
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